CBD, or cannabidiol, is one of the major components in cannabis, and it seems like everyone is selling, pitching, or supporting it these days. Endometriosis, fibromyalgia, PTSD, anxiety, muscular tension, and sleeplessness are among the diseases for which CBD has been promoted by celebrities such as Whoopi Goldberg, Tom Hanks, and Olivia Wilde.
Melissa Etheridge, a Grammy Award-winning singer, claims that CBD helped her cope with the “collateral damage” of chemotherapy during her breast cancer treatment. CBDonline.hk and other cancer communities believe that CBD can help with chronic pain, nausea, vomiting, neuropathy, and appetite loss caused by chemotherapy.
Boom of CBD
According to Forbes, CBD sales in the United States will surpass $20 billion by 2024. Many people may be unaware that the FDA has not approved the use of CBD in any over-the-counter medications. The FDA has not authorized CBD to treat any ailment or disease, including cancer, with one exception. Only one cannabidiol medication, Epidiolex®, has been authorized by the FDA for the treatment of seizures associated with two types of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, as well as tuberous sclerosis complex, a disease in which benign tumors develop throughout the body.
Epidiolex, which is only available by prescription, includes a highly refined version of CBD, according to the FDA. Possible liver damage and the possibility of adverse reactions when the medicine is used with other drugs are among the potential dangers that the FDA requires to be stated on the label.
CBD and Cancer
While some anecdotal evidence of CBD’s benefits for cancer patients has been widely published, scientific study is limited. According to Maurie Markman, MD, President of Medicine & Science at Cancer Treatment Centers of America®, “the scenario creates a problem for clinicians who treat cancer patients” (CTCA).
“There are people who plainly claim it works, as well as groups and medical associations like ASCO (American Society of Clinical Oncology) that indicate it might be beneficial,” Dr. Markman adds. “States claim it’s legal, and the Food and Drug Administration says it’s looking at it. However, the FDA has yet to perform clinical trials to demonstrate its safety and efficacy in comparison to currently available medicines. It’s a challenging scenario for both patients and doctors. Doctors require scientific proof, not anecdotal evidence, to determine whether or not something is safe and effective.”
CBD’s impact on mood swings
CBD is considered to operate by binding to cannabinoid receptors (CB1 and CB2), which are mostly present in the brain and other parts of the body. Both of these CB1 and CB2 are essential parts of the endocannabinoid system, especially in signaling, which is thought to assist control a variety of mental processes, including cognition, sleep, pain, and mood, though its exact role is unknown. CBD may also aid in the regulation of cortisol production, a hormone that helps the body cope with stress.
CBD is available in a variety of forms, including lotions, capsules, chocolates, tinctures, and oils, as well as a vape oil. CBD, unlike another important component of the cannabis plant, tetrahydrocannabinol, or THC, does not get people high. Grocery shops, marijuana dispensaries, petrol stations, pharmacies, and health food stores all carry CBD. It can be consumed, smoked, vaped, or vaporized.
FDA and CBD-derived products
Although the FDA recognizes the “strong public interest in cannabis and cannabis-derived substances,” it maintains that “many unresolved issues regarding the science, safety, and quality” of CBD products remain. According to the agency’s website, it is making “ongoing efforts” to address these inquiries.
An analysis of 22 clinical studies on the use of cannabis and CBD in adults completed over a 19-year period was undertaken by Danish researchers. While CBD may have “therapeutic benefits” on various social and mental problems, they found that the studies had “high risks of bias” and different “methodological flaws.”
According to Dr. Markman, CBD, like all other FDA-approved medications, must be examined through randomized trials, impact on populations, demographics, age groups, and comparisons to previously authorized treatments, just like all other FDA-approved drugs. He claims that no research has yet fulfilled the FDA’s criteria or requirements for approval, which he refers to as “the gold standard.”
CBD effects and side-effects
Experts must conclude that a drug’s advantages “outweigh the known dangers for the intended usage” in order to do so, he argues.
“It doesn’t mean something isn’t valuable without it, but it’s much more difficult to recommend its usage in patients,” Dr. Markman adds. “There are no rules. Simply said, the research isn’t there yet. The underlying issue has been, and continues to be, that you’re dealing with a class of medicines that has been severely under-researched, owing to the fact that it’s illegal under federal law. It’s an unbelievable situation where people are proclaiming how fantastic it is, but we also know about the placebo effect, which is a critical factor to consider. Multiple investigations have also revealed that there is a risk of damage to the central nervous system and cognition. There’s also a huge financial incentive to think about.”
Dr. Markman says he doesn’t dismiss the claims of many doctors and patients who swear by the plant’s therapeutic advantages, but he strongly advises any cancer patient considering taking a CBD product or medical marijuana to speak with his or her oncologist first.
CBD usages, benefits, and applications – Can it help treat?
Of course, many studies have shown positive results in numerous illnesses and diseases. However, a few of the known benefits of CBD are:
- Can Relieve Pain
- Reduce Inflammation
- Relieve Nerve Pain – Neuropathy
- Could Relieve Anxiety and Depression
- Reduce Lower Blood Pressure
- Can Alleviate Cancer – Related Symptoms
- Treats Skin Conditions
- Could Benefit Heart Health
- Protects Against Bone Disease & Broken Bones
- Reduce Risk of Diabetes
- Reduce The Risk of Obesity
- Helps Maintain Brain Health
- As an Antioxidant
- CBD Can Combat Addiction
- CBD Can Improve Mood & Alleviate Mood-Related Disorders
- Help Alzheimer’s
- Reduce Symptoms of PTSD
- Digestive Aid
- Immunomodulatory Effects
- Potential in Treatment
“It’s critical that patients and their doctors address their unique circumstances, including why they want to take it, their safe alternatives, alternatives’ potential side effects, and the various advantages they seek,” he adds. “Hopefully, the information the doctor is using to assist that patient in making a choice is accurate, valuable, and helpful, as well as unbiased and scientifically sound. In the end, each patient must make his or her own decision.”