How Red Light Therapy Can Help to Eradicate Depression Symptoms Fast
If you’re like most people, you’ve probably heard of red and near-infrared light therapy and how it helps treat conditions like depression and seasonal-related depressive symptoms. But why can red light therapy be beneficial for depression, and how does it work? In this blog, we’ll take a look at red light therapy (RLT) and its effects on depression- from how it works to treating symptoms fast. We’ll also recommend the Bestqool red light therapy devices that we know work best for treating depression with RLT. So if you’re looking for an effective treatment option that doesn’t require medication or invasive procedures, red light therapy is a great choice!
How does red light therapy work to treat depression?
Red light therapy for ATP production and brain metabolism
Hypometabolism has been identified in numerous cases of major depressive disorder (MDD). Through positron emission tomography, studies found abnormalities in glucose consumption rates and blood flow in several regions of the human brain with major depression.
While those metabolic abnormalities seem to improve after antidepressant treatment in many areas of the brain, including the anterior cingulate, the amygdala-hippocampus complex, the dorsolateral prefrontal cortex, and the inferior parietal cortex, the photobiomodulation of red light therapy shows potential to improve brain metabolism by stimulating the mitochondrial respiratory chain and encouraging ATP production. A study using near-infrared light on ten patients with major depression, including anxiety, a history of substance abuse, or a post-traumatic stress disorder, found an increase in frontal pole regional cerebral blood flow (rCBF), though with a small change, and a significant improvement of hemispheric emotional valence (HEV).
Red light therapy for inflammation
Studies confirmed that MDD subjects are characterized by increased inflammation and apoptosis, as well as significant elevations of pro- and anti- inflammatory cytokines, including IL-1α, IL-1β, IL-6, IL-8, IL-10, MIP-1α, Eotaxin, GM-CSF, and IFNγ. The following picture also identified the different gene pattern of controlling these cytokines in MDD subjects (green marks in horizontal axis) and controlled ones (purple marks in horizontal axis).
Another study proposed that proinflammatory cytokines have the potential to cause brain abnormalities. Given that the previous factors associated with the pathophysiology of depression have an intense relationship with inflammation, it is intriguing that peripherally released inflammatory cytokines can access the brain and influence all of the relevant pathophysiological domains, as depicted in the following picture.
Red and near-infrared light have been proven to be effective in decreasing synovial IL-6 gene expression in subjects with rheumatoid arthritis, as identified in this study. In another study using near-infrared at 810 nm, as a treatment for pain associated with rheumatoid arthritis, decreased production of a series of proinflammatory cytokines, including TNF-α, IL-1β, and IL-8, while the cognitive function improvement and reduced neuroinflammation by transcranial near-infrared light at 800 nm with an irradiance of at least 60 mW/cm^2 have been found in another experiment on rat model.
Red light therapy for targeting oxidative stress
Research has been conducted to identify a correlation between MDD and vulnerability to oxidative stress. For example, in one study, depression-induced rats showed a significant decrease in glutathione peroxidase (GSH-Px) activity in the cortex. As the most abundant and one of the most important antioxidants in the brain, glutathione (GSH) acts as an indicator of oxidative activity, and GSH-Px enzymes protect against oxidative stress by the way of reducing hydroperoxides and scavenging free radicals. Numerous studies have proven the effectiveness of red light therapy on reducing oxidative stress, and the beneficial effects on oxidative stress can efficiently block the release of harmful ROS and the activation of nuclear factor kappa B (NF-κB), a regulator of immunity, as documented in this report.
How should you use red light therapy for depression treatment?
Near-infrared light is the optimal choice for it can penetrate deeper, directly go through transcantal layer, and target on the brain cells. This research suggests using a near-infrared wavelength of around 810 nm, based on published studies of transcanial laser therapy for stroke in humans and knowledge about the optical properties of human tissue. Another study using a near-infrared wavelength of 800 nm with different levels of dose found that a dose of at least 60 J/cm^2 has a beneficial effect on both improved latancy, indicating some degree of learning ability, and response to probe trials, suggesting a beneficial effect of low-level light therapy on post-injury cognitive function, while using a dose level of 30 J/cm^2 or 120 J/cm^2 didn’t bring improved results on both measurements, which aligns with the biphasic response law. Bestqool suggests, for treatment purposes, standing at a distance of 8 inches to provide sufficient irradiance for penetrating into the brain region and treating for 25 minutes for a sufficient dose. Keeping consistency of treatment by 5 trials per week is important to maintain therapeutic effect.
Why do you need Bestqool red light therapy devices?
If you’re looking for a treatment that is safe and effective, Bestqool red light therapy devices are just right for you. Bestqool products are all FDA-registered and CTL-certified, which distinguishes our products from others from two points of view. First, FDA-cleared assurance and ETL certification secure the safety standards; as with any medical treatment, misusing devices of poor quality can lead to undesired side effects. Second, as a medical-grade FDA Class Ⅱ Medical Device, Bestqool devices ensure the effectiveness of light therapy. It is not redundant to mention that FDA-clearence means the proofreading of the claims of Bestqool devices, as one of process to assess the profession in getting a FDA affirmation.
Bestqool is proud of being able to investigate the technology in this field and produce the devices that focus on the most effective wavelengths and irradiance levels for a wide range of medical conditions. Compared with others, what makes our devices different is not just the efficacy of treatment but also our trustworthiness: all Bestqool products come with a three-year warranty, at least one year longer than any of the counterparts. What is more, with the devotion into LED indutry, the latest of Bestqool model is able to reach as high as 100 mW/cm^2 of direct irradiance output, under safety guard, while the products of other brands, though, may also claim to have the same level of wavelengths and irraidance, what limits the manufacturing is the cooling system to avoid photonic energy transformation into heat or what baffles all of electrical devices — EMFs emitting to have potential harm to human body. Bestqool devices are free of EMFs at three inches of distance and also equipped with a qualified cooling system to provide such a high level of irradiance. We build our confidence in our product quality and client satisfaction, so you can trust us.