Thromboelastography is a noninvasive ultrasound test used to assess clot formation, strength, and dissolution. The assay is an integral part of the pathogenesis of acute coagulopathy. It was first described in 1948 by Dr. Helmut Hartert at the University of Heidelberg. This ultrasound test is not performed on people with active bleeding problems. Rather, it is done on patients with an active bleeding condition.
Thromboelastography is a point-of-care blood test used to determine hemostasis after a craniopharyngioma resection. Using a thromboelastography, physicians can assess the clot’s composition by examining a patient’s clotting factors. A thrombus has four components. Platelets are the initial hemostatic plug, while clotting factors act as glue to keep the platelets together. Other cells provide support for the clut.
According to Coherent Market Insights, the market players are focused on adoption of inorganic growth strategies such as collaborations and agreements to strengthen their position in the thromboelastography market. For instance, in April 2020, Haemonetics Corporation announced the acquisition of enicor GmbH, a manufacturer of whole blood coagulation testing system – ClotPro. This system is expected to strengthen its product capabilities such as TEG 5000 Hemostasis Analyzer and the TEG 6s Hemostasis Analyzer, and offer better products in the market. The ClotPro system reduces the need for annual pipetting and also eliminates reagent handling issues.
There are many thromboelastography devices available, with varying nomenclature and variable definitions. The most common type is the split symmetrical reaction curve, which plots time and amplitude on a vertical axis. It also measures the kinetics of the clot. A split symmetrical reaction curve shows clot strength and clot size. It is used to determine if an initial hemorrhage is progressing into a more advanced coagulopathy.
There are several types of thromboelastography devices. Each device has different characteristics and a range of outputs. In general, however, the most common thromboelastography analyzers use a split symmetrical reaction curve. The curve shows the relationship between amplitude and time. If there is a relationship between the two, the test will be positive. A CT scan is a noninvasive alternative to a blood clot analysis.
The most popular and effective thromboelastography devices are those with a split symmetrical reaction curve. They display the time, amplitude, and strength of clots on a horizontal axis. In addition, they produce a split symmetrical reaction curve, which is a graphical representation of clot strength. For instance, in August 2021, the Irish COVID-19 Vasculopathy Study (iCVS) partnered with DFG, Germany, to initiate studies on sustaining cell activation in COVID-19 patients using the thromboelastography method. This type of thromboelastography is used to assess the health of patients with bleeding disorders.